Which sample is used for measuring hemoglobin concentration in a laboratory CBC?

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Study for the VTNE Laboratory Procedures Test. Use flashcards and multiple choice questions, each question offers hints and explanations, enabling increased understanding and retention. Prepare effectively for your exam!

Multiple Choice

Which sample is used for measuring hemoglobin concentration in a laboratory CBC?

Explanation:
Hemoglobin concentration comes from the Hb contained inside red blood cells, so the sample must include the cellular component that carries Hb. Serum and plasma are the liquid portions of blood with cells removed, so they lack intact red blood cells and cannot directly reflect total Hb. A blood smear is used to assess cell appearance and morphology, not to quantify Hb. In a CBC, a whole blood sample is collected and then the analyzer MPH or lyses the cells to release Hb for measurement, which is why whole blood is the appropriate sample.

Hemoglobin concentration comes from the Hb contained inside red blood cells, so the sample must include the cellular component that carries Hb. Serum and plasma are the liquid portions of blood with cells removed, so they lack intact red blood cells and cannot directly reflect total Hb. A blood smear is used to assess cell appearance and morphology, not to quantify Hb. In a CBC, a whole blood sample is collected and then the analyzer MPH or lyses the cells to release Hb for measurement, which is why whole blood is the appropriate sample.

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