Fibrinogen is produced in which organ?

Fibrinogen is produced in which organ?

• A. Pancreas
• B. Bone marrow
• C. Spleen
• D. Liver

Answer: (D)

Fibrinogen is produced by the liver. It is a soluble plasma glycoprotein synthesized by hepatocytes and released into the bloodstream, where it serves as the precursor to fibrin—the mesh that stabilizes a clot after thrombin converts fibrinogen to fibrin. The liver’s role in producing most coagulation factors means that when liver function is impaired, fibrinogen production can decrease. The other organs listed don’t synthesize fibrinogen: the pancreas makes digestive enzymes, bone marrow produces blood cells, and the spleen has filtering and immune roles but does not generate fibrinogen.

Fibrinogen is produced by the liver. It is a soluble plasma glycoprotein synthesized by hepatocytes and released into the bloodstream, where it serves as the precursor to fibrin—the mesh that stabilizes a clot after thrombin converts fibrinogen to fibrin. The liver’s role in producing most coagulation factors means that when liver function is impaired, fibrinogen production can decrease. The other organs listed don’t synthesize fibrinogen: the pancreas makes digestive enzymes, bone marrow produces blood cells, and the spleen has filtering and immune roles but does not generate fibrinogen.